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Installed 18.104.22.1683 and recompiled my app. I got huge performance hits running it on a device.
I wasn't able to debug and find out exactly what was causing it because, the debugger refused to connect.
I rolled back the installation 22.214.171.124 and the performance was back to normal.
I'm sorry it's not a lot to go on, but, you must have messed something up going from 4.4 to 4.5.
Given the limited information available, I will tentatively mark this bug as a duplicate of Bug 56240 as the likeliest candidate for a matching underlying issue.
*** This bug has been marked as a duplicate of bug 56240 ***