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When resolving dependencies, Xamarin Studio fails to locate a dependency package if the case is incorrect. Visual Studio does not have this issue.
1) Create a new Console Application
2) Add a Nuget reference to ".NET Bio Web Services" - this is a pre-release.
It will fail to find the dependency "NetBioCore-PCL" because Nuget changed the case to "NETBioCore-PCL" (the package id in the original nuspec is correct, but it got changed on upload).
Visual Studio resolves it just fine.
There are some case sensitivity problems with NuGet when not on Windows. The same problem occurs if you try to install the bootstrap NuGet package.
The current workaround, which works for bootstrap and may work for .NET Bio Web Services, is to install NetBioCore-PCL first.
It looks like the stable versions of the NetBioWeb.PCL and NetBioCore.PCL have been fixed on NuGet. I also believe that on a non case sensitive file system this problem should not happen. There are problems on Linux still if you have a case sensitive file system. There is another bug for this. Going to mark this as fixed.